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Toward Personalized Cognitive Diagnostics of At-Genetic-Risk Alzheimer's Disease

Coutrot et al., Proceedings of the National Academy of Sciences, Vol. 116, No. 19, 2019, pp. 9285–9292

Description

The study demonstrating that Sea Hero Quest gameplay patterns can distinguish APOE4 carriers from non-carriers — detecting genetic risk for Alzheimer's disease before any clinical symptoms emerge. The paper where the game succeeded where a conventional memory test failed.

Source

https://www.pnas.org/doi/10.1073/pnas.1901600116

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Contributed

The Academy · May 27, 2026

Discussion

What does this material reveal? Where else does it lead?